Current Mathematical Methods Used in QSAR/QSPR Studies
نویسندگان
چکیده
منابع مشابه
Current Mathematical Methods Used in QSAR/QSPR Studies
This paper gives an overview of the mathematical methods currently used in quantitative structure-activity/property relationship (QASR/QSPR) studies. Recently, the mathematical methods applied to the regression of QASR/QSPR models are developing very fast, and new methods, such as Gene Expression Programming (GEP), Project Pursuit Regression (PPR) and Local Lazy Regression (LLR) have appeared o...
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Some oxidative stress effects, such as lipid peroxidation or the DNA damage, have been extensively assessed and reliable biomarkers have been associated to characterize the degree of the damage, while the attack of reactive oxygen species on proteins and the formation of protein carbonyls were investigated only in the recent years. Taking into account that protein carbonyls may play an importan...
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A drug company has to ensure the quality, safety, and efficacy of a marketed drug by subjecting the drug to a variety of tests [1]. Therefore, drug development is a time-consuming and expensive process. From the initial stage of target discovery, development often takes an average of 12 years [2] and was estimated to cost USD868 million per marketed drug [3]. This high cost and lengthy process ...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2009
ISSN: 1422-0067
DOI: 10.3390/ijms10051978